RT Book, Section
A1 Malinger, Gustavo
A1 Birnbaum, Roee
A1 Krajden Haratz, Karina
A2 Malinger, Gustavo
A2 Monteagudo, Ana
A2 Pilu, Gianluigi
A2 Paladini, Dario
A2 Timor-Tritsch, Ilan E.
SR Print(0)
ID 1194696098
T1 Malformations of Cortical Development: Proliferation Disorders
T2 Timor's Ultrasonography of the Prenatal Brain, 4e
YR 2023
FD 2023
PB McGraw Hill Education
PP New York, NY
SN 9781260136166
LK obgyn.mhmedical.com/content.aspx?aid=1194696098
RD 2024/10/04
AB Key  PointsNeuronal  proliferation,  migration  and  organization  start  relatively  late  in  pregnancy  and  do  not  end  until  after  delivery.In  the  absence  of  associated  malformations,  microcephaly  and  macrocephaly  are  rarely  diagnosed  before  birth  or  even  in  the  newborn.The  majority  of  fetuses  with  a  head  circumference  between  -2  and  -3SD  will  develop  normally.When  a  suspicion  is  raised  genetic  and  pediatric  neurology  consultations  are  indicated.  In  low-risk  patients,  these  signs  may  represent  the  only  possibility  for  prenatal  diagnosis.Exomic  sequencing  if  available  must  be  considered  if  chromosomal  microarray  is  normal  or  inconclusive.