RT Book, Section
A1 Hess, Philip E.
A2 Hess, Philip E.
A2 Li, Yunping
A2 Kowalczyk, John J.
A2 Stiles, Justin K.
SR Print(0)
ID 1199673252
T1 Tranexamic Acid
T2 Obstetric Anesthesia: Quick References & Practical Guides
YR 2023
FD 2023
PB McGraw Hill
PP New York, NY
SN 9781264671465
LK obgyn.mhmedical.com/content.aspx?aid=1199673252
RD 2024/04/20
AB Obstetric  hemorrhage  is  the  leading  cause  of  maternal  mortality  worldwide.  Despite  active  management  during  the  third  stage  of  labor,  postpartum  hemorrhage  (PPH)  remains  a  problem  and  is  increasing  in  the  United  States,  primarily  due  to  the  increasing  incidence  of  atony.1  Tranexamic  acid  (TXA)  is  a  lysine  analogue  and  works  by  binding  to  plasminogen,  thereby  inhibiting  fibrinolysis.  TXA  has  been  used  for  years  in  the  management  and  prevention  of  hemorrhage  in  the  surgical  setting,  including  cardiac,  orthopedic,  and  trauma  surgery.2,3