RT Book, Section A1 Bianchi, Diana W. A1 Crombleholme, Timothy M. A1 D'Alton, Mary E. A1 Malone, Fergal D. SR Print(0) ID 1106395898 T1 Prenatal Diagnostic Procedures T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-144201-5 LK obgyn.mhmedical.com/content.aspx?aid=1106395898 RD 2024/03/29 AB Key PointsPrenatal diagnostic procedures allow prenatal detection of an ever-expanding list of fetal abnormalities by obtaining genetic, biochemical, and physiologic information about the fetus.The specific procedure selected depends upon the gestational age and the information needed.Genetic consultation should be available to help patients choose which diagnostic procedure is optimal for them.Earlier prenatal diagnostic methods have become increasingly more common and are likely to increase in popularity. The most studied of these is CVS. Transcervical and transabdominal techniques are equally effective.Early amniocentesis is not recommended now that compelling evidence regarding its disadvantages has been published.Advances in molecular techniques have led to a declining number of reasons for using percutaneous umbilical blood sampling. It is now rarely the procedure chosen for determining fetal karyotype.Percutaneous umbilical blood sampling is the most direct method of evaluating fetal anemia secondary to severe Rho(D) disease.The majority of invasive diagnostic procedures are associated with low rates of complications commensurate with provider skill and experience.