RT Book, Section
A1 Bianchi, Diana W.
A1 Crombleholme, Timothy M.
A1 D'Alton, Mary E.
A1 Malone, Fergal D.
SR Print(0)
ID 1106396782
T1 Microcephaly
T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-144201-5
LK obgyn.mhmedical.com/content.aspx?aid=1106396782
RD 2024/04/23
AB Key  PointsMicrocephaly  is  characterized  by  a  smaller  than  normal  head  circumference.  A  head  circumference  measurement  of  3  SD  below  the  mean  gives  a  clinically  meaningful  definition  because  it  has  been  associated  with  mental  retardation.Microcephaly  has  been  associated  with  a  number  of  genetic,  infectious,  and  environmental  exposures.Detailed  ultrasound  examination  to  exclude  other  anomalies  is  necessary.A  careful  history  is  needed  when  this  diagnosis  is  suspected.  Likewise,  the  head  circumferences  of  the  parents  should  be  measured.Little  information  is  known  about  the  antenatal  natural  history  of  microcephaly,  especially  during  the  first  and  second  trimesters.The  diagnosis  of  microcephaly  should  not  alter  obstetric  management.Newborns  with  microcephaly  require  an  extensive  work-up  to  determine  the  etiology  of  the  condition.The  long-term  prognosis  and  recurrence  risk  for  microcephaly  is  related  to  its  underlying  cause.