RT Book, Section A1 Bianchi, Diana W. A1 Crombleholme, Timothy M. A1 D'Alton, Mary E. A1 Malone, Fergal D. SR Print(0) ID 1106397041 T1 Hypotelorism T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-144201-5 LK obgyn.mhmedical.com/content.aspx?aid=1106397041 RD 2024/04/19 AB Key PointsDefined as a decreased distance between the medial aspects of the orbital walls.Incidence is approximately 1 in 1220 livebirths.Main concern is its strong association with brain anomalies (especially holoprosencephaly).A fetal karyotype should be offered due to its association with aneuploidy, most commonly trisomy 13.