RT Book, Section
A1 Bianchi, Diana W.
A1 Crombleholme, Timothy M.
A1 D'Alton, Mary E.
A1 Malone, Fergal D.
SR Print(0)
ID 1106398659
T1 Omphalocele
T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-144201-5
LK obgyn.mhmedical.com/content.aspx?aid=1106398659
RD 2024/04/19
AB Key  PointsDefect  in  ventral  abdominal  wall  characterized  by  absent  abdominal  muscles,  fascia,  and  skin.  Defect  is  covered  by  membrane  that  consists  of  peritoneum  and  amnion.Incidence  1  in  4000  to  1  in  7000  livebirths.Principal  sonographic  diagnostic  feature  is  umbilical  cord  insertion  into  the  membrane  covering  the  defect  at  a  location  distant  from  the  abdominal  wall.Differential  diagnosis  includes  gastroschisis,  body-stalk  anomalies,  pentalogy  of  Cantrell,  and  Beckwith–Wiedemann  syndrome.There  is  a  high  incidence  of  both  associated  malformations  and  chromosome  abnormalities.  Prenatal  karyotype  is  indicated.  Fetal  echocardiogram  is  recommended.Serial  prenatal  sonograms  should  be  performed  to  assess  fetal  growth  and  amniotic  fluid  volume.Delivery  at  a  tertiary  care  center  provides  optimal  care  for  the  newborn.  Mode  of  delivery  is  debatable,  except  for  cases  of  giant  omphalocele  or  extracorporeal  liver,  in  which  cesarean  section  should  be  performed.Even  with  primary  surgical  repair,  prospective  parents  should  anticipate  a  long  hospitalization  for  their  neonate.