RT Book, Section
A1 Bianchi, Diana W.
A1 Crombleholme, Timothy M.
A1 D'Alton, Mary E.
A1 Malone, Fergal D.
SR Print(0)
ID 1106399789
T1 Sirenomelia
T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-144201-5
LK obgyn.mhmedical.com/content.aspx?aid=1106399789
RD 2024/04/19
AB Key  PointsIncidence  is  1  in  60,000  livebirths.Results  from  localized  injury  or  insult  to  caudal  end  of  developing  embryo  between  days  13  and  22.Classified  into  7  types  according  to  the  number  of  long  bones  present  in  the  lower  extremity.Associated  with  monozygotic  twinning.First  trimester  sonographic  findings  include  fused  lower  limb  and  increased  nuchal  translucency.Second  trimester  sonographic  findings  include  single  umbilical  artery,  bilateral  renal  agenesis,  oligohydramnios,  and  growth  restriction.Differential  diagnosis  includes  bilateral  renal  agenesis  and  caudal  regression  syndrome.Chromosomes  are  usually  normal.Prognosis  is  extremely  poor  for  extrauterine  survival.