RT Book, Section
A1 Bianchi, Diana W.
A1 Crombleholme, Timothy M.
A1 D'Alton, Mary E.
A1 Malone, Fergal D.
SR Print(0)
ID 1106400918
T1 Liver Tumors
T2 Fetology: Diagnosis and Management of the Fetal Patient, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-144201-5
LK obgyn.mhmedical.com/content.aspx?aid=1106400918
RD 2024/04/23
AB Key  PointsLiver  tumors  account  for  only  5%  of  fetal  and  neonatal  tumors.The  most  common  tumor  is  hemangioma  followed  by  mesenchymal  hamartoma  and  hepatoblastoma.Hemangiomas  can  be  hypoechoic,  hyperechoic,  or  undetectable  and  can  result  in  high-output  failure  polyhydramnios  and  hydrops.Mesenchymal  hamartomas  tend  to  be  cystic  lesions.Hepatoblastomas  are  typically  solid  and  echogenic  and  occasionally  have  calcifications.Hepatoblastoma  can  be  associated  with  Beckwith–Wiedemann  syndrome,  familial  adenomatous  polyposis  coli,  and  rarely,  trisomy  18.Alpha-fetoprotein  levels  may  be  markedly  elevated  in  mesenchymal  hamartoma  and  neuroblastoma.In  utero  cyst  decompression,  rare  mesenchymal  hamartomas  with  extremely  large  cysts  may  be  considered.Transplacental  steroids  may  be  helpful  in  large  hemangiomas  associated  with  high-output  cardiac  failure  or  hydrops.There  is  increased  risk  of  intrauterine  demise  and  stillbirth  in  primary  hepatic  tumors.Neonatal  management  of  primary  hepatic  tumor  is  complicated  and  should  be  performed  at  centers  with  appropriate  expertise.