RT Book, Section
A1 Downs, Levi S.
A1 Carter, Jori S.
A2 Karlan, Beth Y.
A2 Bristow, Robert E.
A2 Li, Andrew J.
SR Print(0)
ID 1106569934
T1 Preinvasive Disease of the Lower Genital Tract
T2 Gynecologic Oncology: Clinical Practice and Surgical Atlas
YR 2015
FD 2015
PB McGraw-Hill Medical
PP New York, NY
SN 9780071749268
LK obgyn.mhmedical.com/content.aspx?aid=1106569934
RD 2024/04/18
AB Over  the  past  3  decades,  the  work  of  population  scientists,  laboratory-based  researchers,  and  clinicians  has  together  promoted  the  understanding  of  the  pathogenesis  of  preinvasive  disease  of  the  lower  genital  tract  and  its  associated  cancers.  Elucidating  the  progression  from  preinvasive  disease  to  invasive  cancer  was  the  first  step  in  implementing  the  Pap  test  as  one  of  the  most  successful  cancer  screening  program  in  developed  nations  and  has  dramatically  lessened  the  impact  of  cervical  cancer  in  the  United  States  and  other  developed  countries.  Furthermore,  with  the  identification  of  the  human  papillomavirus  (HPV)  as  the  principal  and  necessary  cause  of  cervical  cancer,  the  development  and  application  of  HPV  vaccines  will  potentially  further  reduce  the  burden  of  cervical  cancer  and  other  HPV-induced  malignancies.