RT Book, Section A1 Gotsch, Francesca A1 Cruciani, Laura A1 Ghezzi, Fabio A1 Ogge', Giovanna A1 Yeo, Lami A1 Romero, Roberto J. A2 Fleischer, Arthur C. A2 Toy, Eugene C. A2 Lee, Wesley A2 Manning, Frank A. A2 Romero, Roberto J. SR Print(0) ID 1106705718 T1 DOPPLER INTERROGATION OF THE FETAL CIRCULATION T2 Sonography in Obstetrics and Gynecology: Principles & Practice, 7e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071547727 LK obgyn.mhmedical.com/content.aspx?aid=1106705718 RD 2023/09/28 AB This chapter focuses on the Doppler interrogation of the fetal circulation. Other chapters in this book focus on Doppler velocimetry of the uterine arteries and fetal echocardiography. Randomized clinical trials have demonstrated that Doppler examination of the umbilical arteries can reduce perinatal mortality, and therefore this technique is no longer considered investigational. Moreover, the detection of an abnormal Doppler velocimetry of the umbilical artery allows classification of small for gestational age (SGA) fetuses into those who have "placental disease" (defined as an abnormal umbilical artery Doppler waveform) and those who have other conditions that may be responsible for their small size. A fraction of SGA fetuses are diagnosed at term and often do not have any abnormalities of the umbilical artery Doppler, but may have alterations of the cerebral circulation (anterior cerebral artery or middle cerebral artery). Therefore, practitioners need to be familiar with the sampling, interpretation, and clinical significance of these vessels. Similarly, Doppler examination of the venous system (ductus venosus, inferior vena cava (IVC), and umbilical vein) are informative of cardiac function and identify a fetus at risk for impending in utero death. Finally, examination of the peak systolic velocity of the middle cerebral artery has become important in the assessment of fetal anemia. Therefore, this chapter reviews in detail the anatomy, physiology, Doppler waveform morphology, normal ranges, and the interpretation of an abnormal waveform in clinical practice.