RT Book, Section A1 Williams, Felicia N. A1 Lee, Jong O. A2 Pacheco, Luis D. A2 Saade, George R. A2 Hankins, Gary D.V. SR Print(0) ID 1115521253 T1 Burn Injuries in Pregnancy T2 Maternal Medicine YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071824163 LK obgyn.mhmedical.com/content.aspx?aid=1115521253 RD 2024/10/10 AB Despite advances in wound care and critical care medicine, the outcomes of severe burn injuries is still poor. The clinical impact of the injury is often underestimated. Severe burns are followed by a complex catabolic, hypermetabolic response nearly proportional to the size of the injury.1 The response is mediated by a deluge of catecholamines, cortisol, and glucagon to levels up to 10-fold of normal values.2 These elevations persist months to years postinjury, while the clinical manifestations may persist much longer.3,4 The hypermetabolic response to severe burn is associated with increased energy expenditure and energy substrate release from both fat and protein storage leading to profound and persistent whole body catabolism.